Aciphex Drug Interactions

Some of the drugs that can interact with Aciphex include digoxin, ketoconazole, and warfarin. These interactions can cause your body to metabolize the drugs differently than intended, in some cases increasing or reducing the effectiveness of your medications. Before starting treatment with Aciphex, make sure to talk to your healthcare provider about the interactions that apply to you.

Aciphex Medication

An Introduction to Aciphex Drug Interactions

Aciphex^® (rabeprazole sodium) can potentially interact with a number of medications. Some of the medications that may lead to Aciphex drug interactions include:

Atazanavir (Reyataz^®)
Cyclosporine (Gengraf^®, Neoral^®, Sandimmune^®)
Digoxin (Digitek^®, Lanoxin^®, Lanoxicap^®)
Iron
Ketoconazole (Nizoral^®)
Warfarin (Coumadin^®, Jantoven^®).

Aciphex Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Aciphex is combined with any of the drugs listed above.

Atazanavir

Aciphex can substantially decrease the level of atazanavir in the blood (making it less effective). As a result, it is not recommended to take these two medications together.

Cyclosporine

Aciphex could potentially increase the level of cyclosporine in the blood. Check with your healthcare provider before combining cyclosporine with Aciphex.

Digoxin

Aciphex could increase the absorption of digoxin into the blood, perhaps increasing the risk of digoxin side effects and toxicity. Check with your healthcare provider before combining these medications.

(Aciphex Drug Interactions Continued: Page 2)