Artichoke Leaf Extract Dosage
Unlike medications, supplements like artichoke leaf extract are not extensively studied to determine a safe and effective dose. Artichoke leaf extract has been used in some clinical studies, however, and some dosing information is available. For treating indigestion and heartburn, studies used 320 to 640 mg of artichoke leaf extract three times a day. For treating high cholesterol, a dose of 1800 to 1920 mg total per day was used.
The recommended dose of artichoke leaf extract has not been clearly established. Unlike medications, for which the standard doses have been well established in carefully designed studies, there is less information available for determining the best dose for most herbal supplements, including artichoke leaf extract.
With both prescription and non-prescription medications, researchers establish the most effective and safest doses in special studies, known as dose-range studies. These studies are done early in the development of medications, long before they are ever approved. However, because herbal supplements do not need to be approved by the U.S. Food and Drug Administration (FDA), dose-range studies are rarely performed. Without such studies, only vague "trial and error" information is available.
Some information about artichoke leaf extract dosing can be obtained from clinical studies and from practical experience with the supplement. For treating indigestion or heartburn, some studies have used doses of 320 to 640 mg of artichoke leaf extract three times a day. For treating high cholesterol, studies have used doses of 1800 to 1920 mg total per day (split up into two or three smaller doses throughout the day).
Considerations for people taking artichoke leaf extract include the following:
- Because the manufacturing of supplements such artichoke leaf extract is not closely regulated, it is important to choose a trustworthy manufacturer. Your pharmacist is a good source of information regarding which manufacturers are more reputable than others.
- If you have any chronic health problems or take any prescription medications, you should check with your healthcare provider before taking artichoke leaf extract.
- If you are unsure about anything related to your dosage or artichoke leaf extract dosing in general, please talk with your healthcare provider.