Drug Interactions With Cimetidine (Cont.)

Cimetidine Interactions Explained

 
Atazanavir (Reyataz)
Taking cimetidine with atazanavir can decrease the absorption of atazanavir into the body, perhaps making it less effective. Your healthcare provider may need to increase your dose of atazanavir or may suggest an alternative to cimetidine.
 
Chlordiazepoxide (Librium, Limbitrol, Librax)
Cimetidine can increase the amount of chlordiazepoxide in your blood, increasing your chances of experiencing side effects. Your healthcare provider may need to decrease your chlordiazepoxide dosage. Alternatively, your healthcare provider may suggest using one of the cimetidine alternatives.
 
Diazepam (Valium)
Cimetidine can increase the amount of diazepam in your blood, increasing your chances of experiencing side effects. Your healthcare provider may need to decrease your diazepam dosage. Alternatively, your healthcare provider may suggest using one of the alternatives to cimetidine.
 
Itraconazole (Sporanox)
Taking cimetidine with itraconazole can decrease the absorption of itraconazole into the body, perhaps making it less effective. Your healthcare provider may need to increase your dose of itraconazole or may suggest an alternative to cimetidine.
 
Ketoconazole (Nizoral)
Taking cimetidine with ketoconazole can decrease the absorption of ketoconazole into the body, perhaps making it less effective. Your healthcare provider may need to increase your dose of ketoconazole or may suggest a substitution for cimetidine.
 
Metronidazole (Flagyl)
Cimetidine can increase the amount of metronidazole in your blood, increasing your chance of side effects. Your healthcare provider may need to decrease your metronidazole dosage. Alternatively, your healthcare provider may suggest using one of the alternatives to cimetidine.
(Drug Interactions With Cimetidine Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;