If you are taking nonsteroidal anti-inflammatory drugs (NSAIDs) and have a risk for complications with ulcers, a healthcare provider may prescribe Cytotec to help prevent this. The medicine comes in the form of a tablet and is taken by mouth four times daily. It should be taken as long as you are taking an NSAID. Side effects may include diarrhea, nausea, and gas.

What Is Cytotec?

Cytotec® (misoprostol) is a prescription medication approved to prevent stomach ulcers in people taking nonsteroidal anti-inflammatory drugs (NSAIDs). It is used in people who have a risk of developing ulcers or those who are at risk for serious ulcer complications.
(Click Cytotec Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

Cytotec is made by Pfizer, Inc., for G.D. Searle, LLC.

How Does Cytotec Work?

Cytotec is a type of prostaglandin, a hormone-like substance found naturally in the body. Prostaglandins help protect the stomach lining from stomach acid and other harmful substances. Nonsteroidal anti-inflammatory drugs (NSAIDs) block the production of prostaglandins in the body, which is part of the reason these drugs increase the risk for ulcers. Cytotec works to prevent stomach ulcers caused by NSAIDs by protecting the lining of the stomach and decreasing stomach acid secretion.

When and How to Take It

Some general considerations to keep in mind during treatment with Cytotec include the following:
  • This medication comes in tablet form. It is taken by mouth four times a day.
  • You should take Cytotec after a meal and take your last dose of the day at bedtime.
  • Try to take this medication at the same time each day to keep an even level in your blood.
  • To help prevent an ulcer, you will need to take this medicine as long as you are taking an NSAID.
  • For Cytotec to work properly, it must be taken as prescribed.

Cytotec Medication Information

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