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Licorice Drug Interactions
Several medications may cause potentially negative drug interactions with licorice. Some of these medications include blood pressure medications, certain diuretics, and corticosteroids. These licorice drug interactions can result in serious problems, such as low blood potassium and low blood calcium. To avoid these problems, talk to your healthcare provider before taking licorice or licorice supplements with any medications.
Even though it is a dietary supplement, not a "drug," licorice can potentially interact with several medicines. Some of the medicines that may lead to licorice drug interactions include:
- Blood pressure medications
- Certain diuretics, such as:
- Bumetanide (Bumex®)
- Chlorothiazide (Diuril®)
- Chlorthalidone (Thalitone®)
- Ethacrynic acid (Edecrin®)
- Furosemide (Lasix®)
- Hydrochlorothiazide (Esidrix®, HydroDIURIL®, Microzide®, Oretic®)
- Metolazone (Zaroxolyn®)
- Torsemide (Demadex®)
- Corticosteroids, such as:
- Betamethasone (Celestone®)
- Cortisone
- Dexamethasone (Decadron®)
- Fludrocortisone (Florinef®)
- Hydrocortisone (Cortef®)
- Methylprednisolone (Depo-Medrol®, Medrol®)
- Prednisolone (Ovapred®, Pediapred®)
- Prednisone
- Triamcinolone (Kenalog®, Aristospan®)
- Digoxin (Digitek®, Lanoxin®)
- Estrogen medications, such as hormone replacement therapy (HRT) or birth control pills
- Warfarin (Coumadin®, Jantoven®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



