GERD Home > Aciphex Sprinkle Uses

The prescription drug Aciphex Sprinkle is used to treat gastroesophageal reflux disease (GERD). It is approved for use in children ages 1 to 11 years old. In some cases, healthcare providers may prescribe this drug off-label to treat indigestion or heartburn unrelated to GERD. Another unapproved use for Aciphex Sprinkle would include prescribing the drug long-term (more than 12 weeks).

What Is Aciphex Sprinkle Used For?

Aciphex® Sprinkle™ (rabeprazole sprinkle) is a prescription medication that belongs to a group of medicines known as proton pump inhibitors (PPIs). It is approved to treat gastroesophageal reflux disease (GERD) in children ages 1 to 11 years old.

Understanding GERD

GERD is a condition that occurs when stomach acid, or occasionally bile, flows backward from the stomach to the esophagus (the food pipe). This occurs because the sphincter muscle between the esophagus and the stomach either opens at the wrong time or is weak and does not completely close off the opening to the stomach. The backward flow of acid into the esophagus is termed "reflux," which is how the condition gets its name (see What Is GERD? for more information).
When stomach acid flows into the esophagus, it irritates the esophagus, leading to the symptoms of GERD. The symptom most people are familiar with is heartburn, or a burning feeling in the chest and throat.
Heartburn is just one symptom of GERD, however. While most people with the condition experience heartburn, not everyone does. In addition, not everyone with heartburn has GERD. Other possible symptoms include:
  • An acidic or sour taste in the mouth
  • Feeling like food is stuck in the throat
  • Difficulty swallowing
  • Dry cough
  • A hoarse voice
  • A sore throat.
(Click GERD Symptoms to learn about other possible signs of this condition.)
GERD can also occur in infants and children; however, the signs and symptoms may be different, depending in part on the child's age. Young children with GERD may spit up, vomit, or cough. For older children, symptoms can be similar to those experienced by adults (see GERD in Children).
As mentioned, Aciphex Sprinkle is approved for use in children as young as 1 year old. It contains the same active medication as Aciphex (rabeprazole sodium) but, unlike regular Aciphex, comes as a capsule that is opened and sprinkled onto soft foods or into liquids. This makes it easier for children to take.
Regular Aciphex is approved to treat GERD in children 12 years of age and older, as well as adults. It is also approved for the treatment of several other conditions within the esophagus, stomach, and intestines in adults (see What Is Aciphex Used For? for information about regular Aciphex).
Aciphex Sprinkle is only approved for use in children for up to 12 weeks, although PPI medications like this one are often used long-term in certain cases. In clinical studies, it was shown to help heal the lining of the esophagus in children with damage due to GERD. 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation

Topics & Medications


Related Channels

eMedTV Links
Copyright © 2006-2020 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.