GERD Home > What Are H2 Blockers?

H2 blockers are a class of medications used to treat a variety of gastrointestinal conditions. They work by decreasing the amount of acid produced by the stomach. Some of the conditions they can treat include:
H2 blockers are taken by mouth, usually one to four times per day. Common side effects include constipation, nausea, diarrhea, and abdominal pain (stomach pain).
Four prescription H2 blockers are available:
Some of the over-the-counter (OTC) H2 blockers include:
  • Cimetidine (Tagamet HB®)
  • Famotidine (Pepcid AC®, Pepcid® Complete)
  • Ranitidine (Zantac Acid Reducer®).
(Click H2 Blockers for more details on what these medications are used for, what to expect during treatment, and more.)
Written by/reviewed by:
Last reviewed by: Arthur Schoenstadt, MD
Last updated/reviewed:
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