GERD Home > Kapidex

Kapidex is a prescription drug commonly used for the treatment of GERD and erosive esophagitis. It comes in capsule form and is typically taken once a day. The medication works by stopping the production of acid in the stomach. While most people tolerate this medicine well, potential side effects include diarrhea, abdominal pain, and vomiting.

What Is Kapidex?

Kapidex™ (dexlansoprazole) is a prescription medication approved to treat gastroesophageal reflux disease (GERD) and erosive esophagitis (a severe form of GERD in which the lining of the esophagus becomes inflamed and ulcerated).
 
(Click Kapidex Uses for more information, including possible off-label uses.)
 
Starting April 2010, the name for Kapidex was officially changed to Dexilant™. The name was changed because it was too similar to the names of a few other drugs, leading to a few "mix-ups." Please see our Dexilant articles within eMedTV.com for current information about this medication.
 

Who Makes This Medication?

Kapidex is made by Takeda Pharmaceutical America, Inc.
 

How Does Kapidex Work?

Kapidex belongs to a group of medications called proton pump inhibitors (PPIs). The stomach contains tiny pumps (called proton pumps) that produce acid. Kapidex works by binding to the proton pumps, stopping them from producing acid. PPIs are very effective at decreasing acid production, since they work directly at the acid pumps.
 
Kapidex capsules contain tiny delayed-release granules that contain the medication. They are specially designed to release the medication in two different phases. The first "peak" occurs one to two hours after the medication is taken, and the second peak occurs within four to five hours. Additionally, the delayed-release granules are also enteric coated, which means they have a special coating to protect them from stomach acid (since the medication can be destroyed by stomach acid). The coating protects the medication until it reaches the small intestine, where the medication can be absorbed.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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