GERD Home > Neem Side Effects

It is important to know that while taking neem, side effects may occur even though the supplement is a "natural" product. Potential side effects include low or no urine production, yellowing of the skin, and an allergic reaction (symptoms may include itching or hives). There have also been reports of very serious side effects of neem in children, including seizures, loss of consciousness, and coma.

Does Neem Cause Side Effects?

Neem is an herbal supplement used for a variety of different uses (see Benefits of Neem for more information). Many people assume that neem is automatically free of side effects because it is a "natural" product. However, it is reasonable to assume that any natural product with medicinal properties is capable of causing side effects. Neem side effects can be especially dangerous in children.
(This article covers many, but not all, of the possible side effects with neem. Your healthcare provider can discuss a more complete list of neem side effects with you.)

Possible Side Effects of Neem

A few clinical studies have reported side effects with neem. These possible side effects included:
  • Low or no urine production (which may be a sign of kidney damage)
  • Kidney damage
  • Liver damage
  • Yellow skin (jaundice), which may be a sign of liver damage
  • Destruction of red blood cells
  • Allergic reaction, which may cause symptoms such as:


    • A rash or hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.


Be sure to seek immediate medical attention if you think you may be having an allergic reaction to neem.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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