Some of the relatively common side effects of Nexium include such things as headache, diarrhea, and nausea. Other common side effects may include abdominal pain, constipation, and dry mouth. In most cases, side effects associated with Nexium are minor, meaning that they require no treatment or may be easily treated by a healthcare provider. Examples of less-common side effects include allergic reactions, chest pain, back pain, and high blood pressure.
Nexium Side Effects: An Introduction
As with any medicine, there are possible side effects that may occur with Nexium® (esomeprazole magnesium). Yet, not everyone who takes Nexium will have problems. In fact, most people tolerate Nexium well. When people do develop Nexium side effects, they tend to be minor; in most cases, they either require no treatment or can easily be treated by a healthcare professional.
(This article covers many, but not all, of the possible side effects with Nexium. Your healthcare provider can discuss a more complete list of Nexium side effects with you.)
Common Side Effects of Nexium
Nexium has been studied extensively in clinical trials, with over 15,000 people worldwide having been evaluated. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to the side effects that occurred in another group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group not taking the medicine.
The most common side effects of Nexium, occurring in more than 1 percent of patients, were:
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Nexium [package insert]. Wilmington, DE: AstraZeneca Pharmaceuticals LP;2012 January.
Food and Drug Administration. FDA drug safety communication; low magnesium levels can be associated with long-term use of proton pump inhibitor drugs (PPIs) (3/2/11). FDA Web site. Available at: http://www.fda.gov/Drugs/DrugSafety/ucm245011.htm. Accessed March 17, 2011.
Clinical Pharmacology [database online]. Drug Interaction Report. Tampa, FL: Gold Standard, Inc.; 2010. Available at: http://www.clinicalpharmacology.com. Accessed March 17, 2011.
Food and Drug Administration, Center for Drug Evaluation and Research. FDA Drug Safety Communication: Possible increased risk of fractures of the hip, wrist, and spine with the use of proton pump inhibitors (5/25/2010). FDA Web site. Available at: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm213206.htm. Accessed May 28, 2010.
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