GERD Home > More Medications That Interfere With Protonix

Ketoconazole
If you are taking both Protonix and ketoconazole, your body may metabolize them differently than intended. Your healthcare provider may choose to monitor your progress more closely in this case.
 
Methotrexate
Protonix might increase the level of methotrexate in the blood, increasing the risk for methotrexate side effects. Check with your healthcare provider before combining these two medications.
  
Warfarin
If you are taking both Protonix and warfarin, your body may metabolize them differently than intended. Your healthcare provider may choose to monitor your INR (international normalized ratio) and prothrombin time more frequently and adjust your dosages accordingly.
 

Final Thoughts

It is possible that not all Protonix drug interactions were discussed in this article. Therefore, you should talk with your doctor about any potential interactions that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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