Metozolv ODT Drug Interactions
If cyclosporine, digoxin, or an MAOI is taken with Metozolv ODT, drug interactions may occur. This can cause potentially serious problems, such as an increased risk for seizures, extreme drowsiness, and confusion. To help avoid these and other problems, your healthcare provider may monitor the levels of medication in your blood and adjust your dosages accordingly.
An Overview of Interactions With Metozolv ODTMetozolv™ ODT (orally disintegrating metoclopramide) can potentially interact with a few other medications. Some of the medicines that may lead to drug interactions with Metozolv ODT include:
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Diabetes medications
- Digoxin (Digitek®, Lanoxin®)
- Monoamine oxidase inhibitors (MAOIs), such as:
- Other medications or substances that cause drowsiness, such as alcohol, narcotics, sleep medications, or anxiety medications
- Parkinson's disease medications
- Seizure medications.
Metozolv ODT Drug Interactions ExplainedThe following sections explain in detail the potentially negative interactions that can occur when Metozolv ODT is combined with any of the drugs listed above.
Combining Metozolv ODT with an antipsychotic medication may increase the risk of bothersome or disturbing side effects known as extrapyramidal symptoms (EPS). This may also increase the risk of neuroleptic malignant syndrome (NMS), a potentially dangerous side effect of Metozolv ODT. In general, Metozolv ODT should not be taken with antipsychotic medications.