Treating GERD With Metozolv ODT and How It Works

Using Metozolv ODT for GERD

Gastroesophageal reflux disease (GERD) is caused by acid reflux into the esophagus. Acid reflux is a term meaning the backward flow of stomach acid into the esophagus. The stomach is designed to be able to handle the acid it produces; the esophagus, however, is not. If too much stomach acid is in contact with the esophagus for too long, damage to the lining of the esophagus occurs, causing the symptoms of GERD. (Click What Is GERD? for more information.)
A few of the more common GERD symptoms include:
  • Heartburn
  • Feeling like food is stuck in your throat
  • Choking feelings
  • Acidic or sour taste in the mouth
  • Chest pain.
Metozolv ODT is approved for the short-term treatment of GERD (12 weeks or fewer). It works by helping the esophageal sphincter (which controls the opening between the stomach and the esophagus) to close more tightly. Studies have shown that the medication can help relieve symptoms and can also heal erosions and ulcers caused by GERD.
Metozolv ODT is only used to treat GERD in people who have already unsuccessfully tried more conventional GERD treatment, such as antacids or acid reducers.

How Does This Medication Work?

Metozolv ODT has several actions in the digestive tract. It causes the esophageal sphincter (which closes the opening from the stomach up to the esophagus) to become more tight while causing the pyloric sphincter (which closes the opening from the stomach out to the intestines) to relax. It also increases the muscular contractions of the stomach and small intestines.
All of these actions work together to help food move through the stomach more quickly, which is why Metozolv ODT is effective for diabetic gastroparesis treatment. The medication has little or no activity in the colon.
It helps with GERD by preventing the stomach contents from refluxing back up the esophagus, since it increases the tightness of the esophageal sphincter.
When using Metozolv ODT to relieve nausea and vomiting, the drug works by blocking dopamine receptors in the brain. Dopamine can activate the part of the brain that controls nausea and vomiting, and blocking the receptors helps to alleviate these conditions.
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Metozolv ODT Medication Information

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