When it comes to Nexium, uses of the medication include the treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, and Helicobacter pylori (H. pylori) infections. Other uses for Nexium involve using the drug to prevent stomach ulcers from developing in people who regularly take non-steroidal anti-inflammatory drugs (NSAIDs).
Nexium® (esomeprazole magnesium) has been licensed to treat a number of conditions. These Nexium uses may include:
- Treatment of gastroesophageal reflux disease (GERD)
- Treatment of erosive esophagitis
- Prevention of stomach ulcers in those people taking non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen
- Treatment of Helicobacter pylori (H. pylori) infections
- Treatment of pathological hypersecretory conditions (in which stomach acid is greatly overproduced), such as Zollinger-Ellison syndrome.
Using Nexium to Treat GERD and Erosive Esophagitis
Gastroesophageal reflux disease, or GERD for short, is a condition in which stomach acids and other contents of the stomach go back into the esophagus. This can result in GERD symptoms, including the most common symptom of GERD -- heartburn. One of the complications of GERD is erosive esophagitis, which develops when the lining of the esophagus become damaged from the stomach acid.
Nexium has been licensed to treat symptoms of GERD, including heartburn. It has also been licensed to treat erosive esophagitis. Once the esophagus has healed, Nexium may also be used to prevent the return of erosive esophagitis.
Nexium Uses Involving the Prevention of Stomach Ulcers
People who take non-steroidal anti-inflammatory drugs (NSAIDs) on a regular basis are at increased risk for developing stomach ulcers (also known as gastric ulcers). Nexium has been shown to lower the chances of stomach ulcers developing in these people.
Using Nexium to Treat H. Pylori Infections
Helicobacter pylori (H. pylori) is a bacterium known to cause peptic ulcers, which are ulcers in the stomach or first part of the intestines, called the duodenum. Nexium, taken in combination with amoxicillin and clarithromycin, has been shown to kill H. pylori. Therefore, your healthcare provider may recommend Nexium to treat H. pylori if you currently have peptic ulcer disease or have had it within the last 5 years. Treating an H. pylori infection, even if you have no symptoms, will lower the chances of a peptic ulcer occurring.
Nexium for Pathological Hyersecretory Conditions
There are several conditions that cause the stomach to produce too much acid. These conditions include Zollinger-Ellison syndrome, multiple endocrine adenomas, systemic mastocytosis, and "short-gut" syndrome. Nexium works for these conditions by decreasing the production of stomach acid.