Prilosec Interactions

Several drugs may interact with Prilosec, such as Celexa, Valium, and iron supplements. Some of these interactions can alter the amounts of medications in your blood, possibly decreasing their effectiveness or increasing your risk of side effects. Therefore, be sure to talk to your healthcare provider about any drug interactions with Prilosec that may apply to you.

Prilosec Medicine

An Overview of Prilosec Interactions

Prilosec^®(omeprazole) can potentially interact with other medications. Some of the medicines that may lead to drug interactions with Prilosec include:

Ampicillin (Principen^®)
Citalopram (Celexa^®)
Diazepam (Valium^®)
Disulfiram (Antabuse^®)
Escitalopram (Lexapro^®)
HIV medications
Iron supplements
Ketoconazole (Nizoral^®)
Phenytoin (Dilantin^®, Phenytek^®)
Tacrolimus (Prograf^®)
Voriconazole (Vfend^®)
Warfarin (Coumadin^®, Jantoven^®).

Prilosec Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Prilosec is combined with any of the drugs listed above.

Ampicillin (Principen)

Prilosec can decrease the absorption of ampicillin into your bloodstream, perhaps making it less effective. Your healthcare provider may need to increase your ampicillin dose to prevent this interaction from occurring.

Citalopram (Celexa)

Prilosec may increase the level of citalopram in your blood, perhaps increasing your risk of citalopram side effects. Your healthcare provider may need to decrease your citalopram dosage to prevent this.

Diazepam (Valium)

Prilosec can increase the level of diazepam in your blood, possibly increasing your risk of diazepam side effects. Your healthcare provider may need to decrease your diazepam dosage as a result.

(Prilosec Interactions Continued: Page 2)