Prilosec Interactions

There are a number of drugs that may interact with Prilosec, such as Celexa, Valium, and iron supplements. Some of these Prilosec interactions can alter the amounts of medications in your blood, possibly decreasing the effectiveness of the drugs or increasing your risk of side effects. Therefore, be sure to talk to your healthcare provider about any drug interactions with Prilosec that may apply to you.

 

An Overview of Prilosec Interactions

Prilosec® (omeprazole) can potentially interact with other medications. Some of these medicines that may lead to Prilosec drug interactions include:
 

 

Prilosec Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Prilosec is combined with any of the drugs listed above.
 
 
Ampicillin (Principen)
Prilosec can decrease the absorption of ampicillin into your bloodstream, perhaps making it less effective. Your healthcare provider may need to increase your ampicillin dose.
 
Atazanavir (Reyataz)
Prilosec can decrease the level of atazanavir in your blood, perhaps making it less effective. Your healthcare provider may need to increase your atazanavir dose.
 
Citalopram (Celexa)
Prilosec may increase the level of citalopram in your blood, perhaps increasing your risk of citalopram side effects. Your healthcare provider may need to decrease your citalopram dosage.
(Prilosec Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;