Prilosec is commonly prescribed for conditions related to the esophagus, stomach, and intestines. These conditions can include things such as GERD, duodenal ulcers, gastric ulcers, and H. pylori infections. Prilosec belongs to a class of medications known as proton pump inhibitors, and works by decreasing the amount of acid in your stomach by blocking acid production sites. Common side effects include headaches, stomach pain, and upper respiratory infections.

What Is Prilosec?

Prilosec® (omeprazole) is a prescription medication used to treat several conditions related to the esophagus, stomach, and intestines. It is part of a class of drugs known as proton pump inhibitors (PPIs).
Over-the-counter Prilosec OTC® (omeprazole magnesium) is also available for treating heartburn.

What Is It Used For?

Some of the uses of prescription Prilosec include treating:
  • Duodenal ulcers (ulcers in the first part of the intestine after the stomach).
  • Helicobacter pylori infections associated with duodenal ulcers -- The medication is used in combination with antibiotics to eliminate H. pylori bacteria in the stomach, helping to heal duodenal ulcers.
  • Benign (noncancerous) gastric ulcers (or stomach ulcers).
  • Gastroesophageal reflux disease (GERD) -- Prilosec helps to treat GERD by relieving heartburn and healing esophagitis (damage to the esophagus).
  • Pathological hypersecretory conditions -- The medication helps treat these conditions (when too much stomach acid is produced), such as Zollinger-Ellison syndrome.
Over-the-counter Prilosec OTC is approved to treat frequent heartburn that occurs at least twice a week.
(Click Prilosec Uses for more information, including possible off-label uses.)
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Prilosec Medicine

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