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Protonix Side Effects

In the case of Protonix, side effects most commonly include such things as headache, diarrhea, nausea, flatulence, abdominal pain, and insomnia. Other common side effects of Protonix may include vomiting, high sugar levels, and burping. There are many possible side effects of Protonix, but most of them are rare, meaning they occur in less than 1 percent of patients. Examples of rare Protonix side effects include allergic reaction, swelling under the skin, and chills.

 

Protonix Side Effects: An Introduction

As with any medicine, there are possible side effects associated with Protonix® (pantoprazole sodium). Not everyone who takes Protonix will experience Protonix side effects. In most cases, Protonix side effects are minor, which means that they require no treatment or are easily treated by your healthcare provider.
 
(The side effects discussed below are NOT a complete list of side effects reported with Protonix. Your healthcare provider can discuss a more complete list of Protonix side effects with you.)
 

Common Protonix Side Effects

Protonix has been studied extensively in clinical trials, with over 11,000 people worldwide having been evaluated.
 In these studies, side effects are always documented. The most common side effects of Protonix were:
 
  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Insomnia
  • Rash
  • Burping
  • High blood sugar levels (hyperglycemia)
  • Vomiting
  • Abnormal liver function tests.
 

Other Protonix Side Effects

There are other possible Protonix side effects that can occur. In previous clinical studies, these side effects occurred in more than 1 percent of patients.
 
Some of these possible Protonix side effects include, but are not limited to:
 
  • Anxiety
  • Pain in a joint (arthralgia)
  • Lack of strength and energy (asthenia)
  • Back pain
  • Bronchitis
  • Chest pain
  • Constipation
  • Increased cough
  • Dizziness
  • Indigestion (dyspepsia)
  • Flu syndrome
  • Gastroenteritis
  • High fat levels in the blood (hyperlipidemia)
  • Migraine
  • Neck pain
  • Sore throat (pharyngitis)
  • Irritation and inflammation of the nasal passages (rhinitis)
  • Respiratory tract infection
  • Urinary tract infection (UTI).
 

Rare Protonix Side Effects

There are other possible Protonix side effects that can occur. These rare side effects occur in less than 1 percent of patients. For these side effects, it is difficult to tell whether the side effect is because of the medication or something else.
 
Some of these possible rare Protonix side effects include, but are not limited to:
 
 

Protonix Side Effects: Summary

It is possible that you may experience some or none of these Protonix side effects. Make sure to let your healthcare provider know if you develop any side effects. Also, let your healthcare provider know if you develop something that "just does not seem right." While it may not be a Protonix side effect, your healthcare provider will work to diagnose and treat the problem.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;