Antipsychotics
Combining
Reglan with an
antipsychotic medication may increase the risk of very bothersome or disturbing side effects known as
extrapyramidal symptoms (EPS). In general, Reglan should not be combined with antipsychotic medications.
Cyclosporine
Reglan may increase the amount of cyclosporine that is absorbed into the bloodstream. This could increase the chance of cyclosporine toxicity. Your healthcare provider may need to measure the level of cyclosporine in your blood and adjust your cyclosporine dosage, especially when you start or stop taking Reglan.
Diabetes Medications
Reglan helps food move through the stomach more quickly. While this is usually a desirable result in people with
diabetic gastroparesis, your healthcare provider may need to adjust the dosage and/or the timing of your
diabetes drugs to account for this change.
Digoxin
Reglan may decrease the amount of digoxin that is absorbed into your bloodstream, perhaps making it less effective. Your healthcare provider may need to measure the level of digoxin in your blood and adjust your digoxin dosage, especially when you start or stop taking Reglan.
Monoamine Oxidase Inhibitors (MAOIs)
Taking Reglan with an MAOI may cause dangerous side effects. In general, it is best to avoid taking Reglan with an MAOI.
Other Medications That Cause Drowsiness
Combining Reglan with other medications that are prone to cause drowsiness may lead to severe drowsiness, confusion, or memory loss. Check with your healthcare provider before taking such medications together.
Parkinson's Disease Medications
Reglan blocks dopamine receptors, which may make many
Parkinson's disease medications less effective. Check with your healthcare provider before combining Reglan with any Parkinson's medication.
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