Drug Interactions With Sucralfate

Taking certain medications in combination with sucralfate may result in negative interactions. For example, medications such as "azole" antifungals, cimetidine, and digoxin can bind to sucralfate in the digestive tract, making the medications less effective. To avoid possible drug interactions, make sure to tell your healthcare provider about any other medicines you are taking.

An Overview of Sucralfate Interactions

Sucralfate (Carafate®) can potentially react with several other medications. Some of these medicines that may lead to sucralfate drug interactions include:
  • Aluminum-containing antacids
  • Anagrelide (Agrylin®)
  • "Azole" antifungals, such as:
    • Fluconazole (Diflucan®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Posaconazole (Noxafil®)
    • Voriconazole (VFEND®)

Sucralfate Drug Information

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