Zegerid Side Effects

Although most people have no problems with Zegerid, adverse reactions are possible. The most commonly reported side effects of Zegerid include headaches, diarrhea, and abdominal pain (stomach pain). Notify your healthcare provider right away if you experience serious side effects, such as difficulty breathing, seizures, or an unexplained increase in urination.

An Introduction to Zegerid Side Effects

As with any medicine, Zegerid® (omeprazole/sodium bicarbonate) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with Zegerid. Your healthcare provider can discuss a more complete list with you.)
 

Common Side Effects of Zegerid

Interestingly, the information on potential side effects in the prescribing information for Zegerid comes largely from studies that used plain omeprazole (Prilosec®), rather than omeprazole/sodium bicarbonate. However, possible side effects are expected to be similar for both medications.
 
Some information from studies with Zegerid is available, but these studies were performed in severely ill people (typically people in the intensive care unit), and the results are therefore probably not applicable to the general public.
 
Based on the results of studies with plain omeprazole, the most common bothersome (but usually not dangerous) side effects of Zegerid may include:
 
  • Headaches -- in up to 6.9 percent of people
  • Abdominal pain (stomach pain) -- up to 5.2 percent
  • Diarrhea -- up to 3.7 percent
  • Upper respiratory tract infections, such as the common cold -- up to 1.9 percent
  • Dizziness -- up to 1.5 percent
  • General weakness -- up to 1.3 percent
  • Constipation -- up to 1.1 percent
  • Coughing -- up to 1.1 percent
  • Back pain -- up to 1.1 percent.
     

Zegerid Medication Information

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